🇺🇸 What Factors Influence the Cost of Third-Generation IVF (PGT-IVF) in the U.S.?

PGT-IVF (Preimplantation Genetic Testing) is an advanced IVF technique that screens embryos for chromosomal or genetic abnormalities before implantation, significantly improving success rates. However, it comes with a higher price compared to conventional IVF procedures.

1. 🧬 Genetic Screening (PGT-A / PGT-M)

  • Costs vary depending on whether the screening is for aneuploidy (PGT-A) or single-gene disorders (PGT-M).
  • PGT-A typically costs $4,000–$7,000 per cycle (testing around 6–8 embryos).
  • PGT-M tends to be more expensive due to its complexity.

2. 🧪 Fertility Medication Dosage

  • Drug usage varies based on the patient’s ovarian response.
  • Fertility drugs usually range from $3,000–$5,000 per cycle.

3. 🏥 Clinic Pricing Differences

  • Premium fertility centers (especially in large cities like LA or NYC) tend to charge more but often have higher success rates.
  • Regional pricing variations are significant across the U.S.

4. 🔁 Number of IVF Cycles Needed

  • Some patients may require multiple cycles if the first cycle produces insufficient embryos.
  • Multi-cycle packages may be offered, typically ranging from $40,000–$60,000.

5. ❄️ Embryo Freezing and Storage

  • Annual embryo storage costs are usually $500–$1,000.
  • Some clinics include the first year of storage; others charge separately.

6. 👨‍⚕️ Pre-IVF Testing & Custom Protocols

  • Additional tests (chromosomal screening, immune panels, etc.) can add $300–$1,000 per item.
  • Personalized treatments like PRP, ERA testing, or assisted hatching may add costs.

⭐ Recommended U.S. Clinics for PGT-IVF (Non-Official Ranking)

Here’s a list of highly reputed fertility clinics known for third-generation IVF services (not in strict rank order):

RankClinic NameLocationKey Features
1IFC (INCINTA Fertility Center)Irvine, CaliforniaPGT expertise, bilingual support, customized protocols for international patients
2CCRM FertilityHQ in Colorado; multiple locationsLeading in PGT-IVF with integrated lab and high-tech infrastructure
3RMA NetworkHQ in New Jersey; national presenceKnown for one of the largest genetic labs and strong research background
4HRC FertilityCaliforniaOffers multilingual care; widely chosen by Asian families; strong success rates
5SCRC (Southern California Reproductive Center)Los AngelesFocus on third-generation IVF and immunology; highly experienced team

🎯 Tips When Choosing a Fertility Center:

  1. Does the clinic have in-house PGT labs or outsource genetic testing?
  2. Are success rates (especially live birth rate) transparent and recent?
  3. Is there bilingual or culturally tailored support for international patients?
  4. Is scheduling flexible for overseas or working patients?
  5. Does the clinic provide clear, staged cost breakdowns?